Fungal BLAST and Model Organism BLASTP Best Hits: new comparison resources at the Saccharomyces Genome Database (SGD)

نویسندگان

  • Rama Balakrishnan
  • Karen R. Christie
  • Maria C. Costanzo
  • Kara Dolinski
  • Selina S. Dwight
  • Stacia R. Engel
  • Dianna G. Fisk
  • Jodi E. Hirschman
  • Eurie L. Hong
  • Robert S. Nash
  • Rose Oughtred
  • Marek S. Skrzypek
  • Chandra L. Theesfeld
  • Gail Binkley
  • Qing Dong
  • Christopher Lane
  • Anand Sethuraman
  • Shuai Weng
  • David Botstein
  • J. Michael Cherry
چکیده

The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org/) is a scientific database of gene, protein and genomic information for the yeast Saccharomyces cerevisiae. SGD has recently developed two new resources that facilitate nucleotide and protein sequence comparisons between S.cerevisiae and other organisms. The Fungal BLAST tool provides directed searches against all fungal nucleotide and protein sequences available from GenBank, divided into categories according to organism, status of completeness and annotation, and source. The Model Organism BLASTP Best Hits resource displays, for each S.cerevisiae protein, the single most similar protein from several model organisms and presents links to the database pages of those proteins, facilitating access to curated information about potential orthologs of yeast proteins.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Saccharomyces Genome Database (SGD) provides tools to identify and analyze sequences from Saccharomyces cerevisiae and related sequences from other organisms

The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org/), a scientific database of the molecular biology and genetics of the yeast Saccharomyces cerevisiae, has recently developed several new resources that allow the comparison and integration of information on a genome-wide scale, enabling the user not only to find detailed information about individual genes, but also to make conne...

متن کامل

The new modern era of yeast genomics: community sequencing and the resulting annotation of multiple Saccharomyces cerevisiae strains at the Saccharomyces Genome Database

The first completed eukaryotic genome sequence was that of the yeast Saccharomyces cerevisiae, and the Saccharomyces Genome Database (SGD; http://www.yeastgenome.org/) is the original model organism database. SGD remains the authoritative community resource for the S. cerevisiae reference genome sequence and its annotation, and continues to provide comprehensive biological information correlate...

متن کامل

Saccharomyces genome database informs human biology

The Saccharomyces Genome Database (SGD; http://www.yeastgenome.org) is an expertly curated database of literature-derived functional information for the model organism budding yeast, Saccharomyces cerevisiae. SGD constantly strives to synergize new types of experimental data and bioinformatics predictions with existing data, and to organize them into a comprehensive and up-to-date information r...

متن کامل

Integrating functional genomic information into the Saccharomyces Genome Database

The Saccharomyces Genome Database (SGD) stores and organizes information about the nearly 6200 genes in the yeast genome. The information is organized around the 'locus page' and directs users to the detailed information they seek. SGD is endeavoring to integrate the existing information about yeast genes with the large volume of data generated by functional analyses that are beginning to appea...

متن کامل

Bioinformatics Research on a New Protein Given the Sequence

In this report, various bioinformatics tools were employed to find sequence and structure homologs of a protein given its sequence. These tools include BLAST, PSI-BLAST, PFAM, ClustalW, T-Coffee, SAM-T99, SAM-T02, SingalP, TMHMM, and RasMol. Further information about genetic and metabolic functions of this protein was gathered from multiple online databases, including Saccharomyces Genome Datab...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Nucleic Acids Research

دوره 33  شماره 

صفحات  -

تاریخ انتشار 2005